limited precision, because all the motors are controlled not by counting rotations but by a simple timeout function (I've tried to build a simple 2D printed with WeDo kit and it failed even to draw a square) limited mobility, unless you enjoy running around with your laptop in hand In general, WeDo feels like Mindstorms little brother - and by little I mean much more restricted and much less intuitive.
I happen to have the WeDo kit and I just got an extra USB hub and motion sensor for it.